The GTM Chemistry Framework
A go-to-market discovery method for teams that have to make decisions before they have data to make them with. Four elements, seven reactions, and the headline, positioning and warm intro map that come out the other side.
I know this is not a new idea. A discovery grid like this one is well known and usually lives in a spreadsheet. This is the fast version of it, with a visualization people enjoy, which is what I bring to workshops.
1. What the GTM Chemistry Framework is
Everyone on a go-to-market team has opinions about customers, competitors, partners and who to call. Those opinions live in different heads, in different words, and never get compared side by side. So the team argues about tactics without having agreed on the diagnosis.
This method fixes that with a constraint: each area of discovery gets exactly one question and one sentence. One sentence is short enough that a room can align on it, and specific enough that it can be combined with the other three.
The combination is the point. Knowing your ideal customer is a diagnosis. Knowing your competitor is a diagnosis. Knowing both, in one sentence each, gives you a headline, because a headline is a promise of the outcome your customer wants, aimed at the gap your competitor left open.
Elements are diagnoses. Compounds are decisions. This exists to get you from one to the other in a single session.
2. Who it is for: early-stage startups, hackathon teams and pre-seed founders
I built this for teams that have to write positioning before they have the numbers that would justify it. If you have thousands of customers and a working analytics stack, go read the data instead. This is for the stage before that, when the honest answer to "who is this for" is a guess that nobody has written down.
When it will not help you
Skip it if you already have a positioning document the team agrees on, if you have enough customers that qualitative guessing is worse than reading your funnel, or if your problem is execution rather than direction. This method produces a diagnosis and copy. It will not fix a product nobody wants, and it will not tell you whether your pricing is right.
3. How to use it
Same four steps for every element. The steps matter more than the tooling. A whiteboard, a Miro board and a shared doc all work.
4. The four elements of GTM discovery
Four areas of discovery, four questions, four symbols. Everything downstream is built out of these.
Who is your ideal customer, and why wouldn't they use your product?
Who are your strongest competitors, and what makes them strong?
Who are the partners you want building alongside you?
Who do you need to talk to in order to leverage your product?
Read the legend as a sentence and you have the shape of a go-to-market story: for whom, against whom, with whom, through whom. The four elements are the four prepositions.
Who is your ideal customer, and why do you think your ideal customer wouldn't use your product?
The second half does the work. Teams can describe their ideal customer fluently and have never once written down the reason that customer says no.
Who are your strongest competitors, and what makes them so strong?
Name the strength honestly before you look for the gap. A team that cannot articulate why the leader is winning will invent a weakness that is not there.
Who are the partners you want building alongside you?
Partners are distribution you do not have to buy. The test is not whether the logo is impressive, it is whether their builders overlap with your ideal customer.
Who are the people you need to talk to in order to leverage your product?
This element is the only one that ends in a calendar entry. If the sentence does not name a person and a date, it is not finished.
5. The structural formula
Drawn the way a skeletal formula is drawn. The four elements sit in a row along the top, and every bond drops to the compound that pair produces. Depth carries meaning: two elements standing next to each other bond in the shallow tier, and the two at opposite ends of the row bond at the bottom of the sheet.
The bottom tier is the one teams never reach on their own. Ic and Bd sit at opposite ends of the row, so nobody thinks to put the ideal customer and the personal network in the same sentence, and that combination is the warm intro map: the named people who can get you in front of the buyer you just described. The two middle-tier bonds have the same property, which is why the drawing puts them below the obvious ones rather than beside them.
6. The seven compounds
Each reaction reads as a formula: two outcome sentences in, one artifact out. The first three are the ones teams find on their own. The next three are the ones the drawing above puts in the lower tiers.
7. A worked case
CatTrade is a fictional trading platform whose ideal customer already uses the market leader, DogTrade. The whole session, filled in.
Open the CatTrade case · four elements filled, three compounds produced
Ic · ICP discovery
Cp · competitors discovery
Pt · partners discovery
Bd · BD discovery
The compounds that came out
Everything you love about trading. Fees you won't find on DogTrade. Fully regulated.
What the reaction surfaced: "nobody knows us" is a distribution problem, because headlines do not reach people who never land on your site. "They already trust the incumbent" is a messaging problem, because headlines have to prove safety and give one concrete reason to switch. Separate the two before writing a single line of copy.
8. The launch compound
The final reaction. Every slot in it is already answered by one of the four elements, so a blank tells you which element to go back to.
One product, one audience, one channel, one hook, one metric, one next move. Anything that does not fit the sentence is next quarter's problem.
9. Prompts to run the reactions
Once the four elements are answered, the sheet is a prompt. Paste the two outcome sentences, name the reaction, ask for the artifact.
The six reactions, written out. Copy the one you need.
Hey Claude, here are two outcomes from my GTM Chemistry sheet. ICP: [paste]. Competitors: [paste]. React them and write five landing page headlines that promise the outcome my ICP actually wants while attacking the gap the competitor left open. No claim I cannot back with the proof point in the ICP sentence.
Hey Claude, react my Competitors outcome with my Partners outcome: [paste both]. Give me one positioning line that claims the turf the incumbent left open inside that ecosystem, and the three proof points I would need to defend it.
Hey Claude, react my ICP outcome with my BD outcome: [paste both]. Build the warm intro map: who to reach, through whom, what I give before asking, and a first message for each path that does not read like a sales email.
Hey Claude, based on the reaction Bd + Pt from my GTM Chemistry sheet: [paste both]. Rank the partnership targets by who can actually sign, then draft the first outreach for the top three and tell me what I am offering each one before I ask for anything.
Hey Claude, react Cp + Bd: [paste both]. Give me eight questions for the people who already know why customers switch, phrased so they answer honestly instead of hearing a pitch.
Hey Claude, here are all four outcomes from my GTM Chemistry sheet: [paste]. Write the GTM narrative in one paragraph, for whom, against whom, with whom and through whom, short enough that anyone on the team can repeat it from memory.
The templates do the hard part. A model given two vague sentences returns vague copy, which is the whole reason the outcome templates are rigid.
10. Where it came from, and what is actually new
The ingredients are not new. ICP discovery, competitive analysis, partner mapping and business development are standard go-to-market blocks, and crossing quadrants to generate strategy has an ancestor in the TOWS matrix. What I have not found elsewhere is this combination: four discovery areas compressed into one rigid sentence each, with the pairwise combinations mapped to named artifacts rather than general findings. The classic methods stop at diagnosis. This one is built to force output.
It started on a Miro board, four quadrants along the top and lines converging into the artifacts underneath. The funnel made the logic obvious and the chemistry metaphor made it teachable. It is a living document: as I run it with more teams, some of these templates will get thrown out.
Want to run this with your team? Find me on Twitter / X. If you run it yourself, I would genuinely like to see what came out.